Yeah you’d have to handwire to get the bottom row of the M0116 on custom. The 60% PCBs I know of that support ALPS are either a regular ANSI or AEK layout. Honestly I would say to go with the AEK layout if you can. Not only would it make getting a plate & PCB much easier, you would also have a proper space bar with a centered switch.
For me the small off center switched spacebar on the M0116 is what killed it for me. I tried everything but not matter what I did it binded very easily on any presses other than ones on the right side. I could see that type of spacebar being a real problem on a custom build.