After all those boards I have built so far I (almost) found my favourite layout.
I really love my 60%-builds with 2 x 2U shift, and the lowest alpha row moved 0.25U to the left.
Now I am looking for a 65%-PCB with that option, because five more keys would be the cherry on top.
I do not know of such a build, though it seems that the existence of a 2u left shift 60% was to accommodate arrow keys. A 65% solves that issue, making the left shift somewhat of a redundant fix.
I also like a 60% with a 2u left shift because it allows for arrow keys on a 60%, but as roosky15 pointed out, a 65% board already has arrow keys, so I don’t think anyone would go out of their way to make a 65% that uses one.